In situ bladder cancer cases are included in the NPCR Cancer Surveillance System analytic file.

• A. Not collected
• B. Only invasive cancer
• C. True
• D. False

Answer: (C)

In cancer surveillance, the analytic file is designed to capture the full spectrum of reportable neoplasms, not just invasive ones. For bladder cancer, carcinoma in situ is a noninvasive but malignant-acting lesion and is reportable to population-based registries. Because of that, NPCR collects and includes these in situ bladder cancers in the analytic file so analyses reflect the complete burden of bladder neoplasia, allowing accurate incidence and trend assessment and better understanding of progression risk. This is why the statement is true.