The primary quality-control concerns of central registries involve how complete case ascertainment is and how complete and accurate the collected data are.

• A. Not sure
• B. Not applicable
• C. True
• D. False

Answer: (C)

In central registries, the main quality-control focus is on capturing every cancer case that occurs (complete case ascertainment) and on making sure the data collected for each case are both complete and accurate. This matters because if some cases are missed, incidence and trend estimates become biased. If data fields are incomplete or incorrect, analyses of stage, histology, treatment, and outcomes become unreliable. So this statement is true: the primary quality-control concerns are the completeness of case ascertainment and the completeness and accuracy of the collected data.